With sous vide, if your set point is 125F, it will never cook beyond that point, regardless of how long you SV it. The longer you SV, the more tender the protein becomes, and some proteins can become mushy and fall apart if cooked too long. SV is very lenient as far as cooking time goes. The protein does not get the Maillard reaction from SV, so after SV, broiling, grilling, pan frying, or searing with a chef's torch adds that touch. I typically SV ribs and roasts with SPOG at 143F for 12 - 16hrs or longer, dry with paper towels, then sauce, smoke, and grill them. They are already completely cooked coming out of the SV so it doesn't take very long on the grill, depending on how hot the grill is. Grilling/broiling "tightens" the protein and improves the mouth feel.
Also, some people are sensitive to the color of proteins...ie, if it's red, it's undercooked. My wife is like that, hence my 143F cooking temp.