Matt:
I am not trying to be condescending. I didn't go back through the whole thread, it is pretty long. I wrongly assumed you had just added onto an ongoing and meandering thread.
It sounds like you are covering all the possible causes. But, I have owned probably 15 Q grills and only found one bad regulator on one of them. And it still worked fine, it just made a slight "fluttering" sound when in use which is not uncommon. But, I have dealt with the vapor lock issue. It is a symptom of the new OPD on the 20lb bulk tanks. They are designed to detect a large leak and when you open them with the burners turned on or if you simply open them real quickly, they shut down flow thinking a massive leak has just occurred. But, no, it shouldn't happen with a 1lb container or if you don't turn your tank off between uses. I have experienced this on both Genesis grills and Q grills, but it seems to be a bigger issue with Q grills. Shutting down the burners, then shutting down the tank, disconnecting the hose from the tanks, waiting a minute or two, reconnecting the tank, then slowly opening the valve on the tank, then turning on the burner and lighting it always fixed the low flame issue unless it was something else such as plugged burner holes.
Drilling out the orifice hole will likely boost your heat output and depending on how much you ream it out, it could be a lot. The one to ask on doing that kind of mod is probably Larry Micheals. He has some good experience with doing that and can lead you in the right direction.
How hot does the lid thermometer say your grill is getting when fully heated up?