Smoke doesn't get into the meat, at least not that much. The smokering is evidence of about how far in it could possibly penetrate. It is not absorbed into the meat per se, but rather, in being deposited on the meat, is being adsorbed to a small degree. When meat is pulled or sliced, smoke particles deposited on the outer parts are distributed to previously unexposed inner parts, just as are rub and bark, adding their flavors to more of the overall product. So, to answer your question, no, I wouldn't say rubs prevent anything smoke-wise. Think of what we do with the WSM more as using smokewood in barbecuing to impart additional flavor, rather than how smoke is used in a cold-smoking or curing process.